To take this topic a little bit further, I've always loved the 1 vs. many fight scenes -- obviously in many old Shaw Brothers you would see the heroes fighting off throngs of Manchu soldiers. All of the martial arts stars each had a big scene like this at some point as well, such as:

Bruce Lee taking on the Japanese school in Chinese Connection

Jet Li's version of that scene in Fist of Legend

Jackie Chan vs. the Axe Gang in Drunken Master

Stephen Chow at the end of Kung Fu Hustle (very comical)

Neo vs. a plethora of Mr. Smiths in the 2nd Matrix movie (too much CGI)

I think Tony Jaa has upped the ante and topped them all with the joint breaking scene in The Protector -- that scene still makes me wince -- and the sound effects were particularly wicked and just added to the brutality, much like the sounds of the baseball bats did in the scene in Casino where Joe Pesci and his brother got whacked.

What's your favorite 1 vs. many scene?